Mabalacat, Pampanga is where the northern end of the North Luzon Expressway is located, specifically in Brgy. Sta. Ines, 88 kilometers from Manila. From here, motorists going further north can go through the traditional route to the west along MacArthur Highway (passing through the previously mentioned Bamban Bridge) or they can go east towards Concepcion, Tarlac.
As part of the Central Luzon infrastructure development, there are plans to extend the North Luzon Expressway to Tarlac City and to connect it with the proposed Subic-Clark Expressway somewhere in Bamban, Tarlac.